Which cells are primarily responsible for bone formation?

Osteoblasts are the cells primarily responsible for bone formation. They play a crucial role in synthesizing and mineralizing the bone matrix. These cells originate from mesenchymal stem cells and are characterized by their ability to produce collagen and other proteins that constitute the organic part of the bone tissue. Once they secrete the bone matrix, osteoblasts become trapped within the matrix they create and differentiate into osteocytes, which help maintain bone tissue.

Osteoblasts carry out key activities that contribute to the growth and healing of bones, including the deposition of calcium phosphate, which is essential for the mineralization process that gives bone its strength and rigidity. Their activity is vital during both the development of the skeletal system in growing individuals and the remodeling of bone in adults.

In contrast, other cell types mentioned in the options have different roles. Chondrocytes are involved in the formation of cartilage, which is a precursor to bone in the development of the skeleton. Osteoclasts are responsible for bone resorption, breaking down bone tissue, which is essential during bone remodeling and calcium homeostasis. Fibroblasts are associated with the formation of connective tissue fibers and do not directly contribute to bone formation.

Thus, the role of osteoblasts