What type of bond rejoins a newly synthesized DNA strand after a UVR-induced lesion is repaired?

The correct answer is identified as a phosphodiester bond, which plays a crucial role in the structural integrity of DNA. When repairs occur in DNA, particularly in the context of lesions induced by UV radiation, the repair mechanisms often involve the excision of damaged nucleotides and the synthesis of new ones.

During the DNA repair process, particularly through nucleotide excision repair (NER), the damaged segment of DNA is removed. After the excised section is replaced with new nucleotides, the newly synthesized DNA strands must be linked to the existing DNA backbone. This is accomplished by forming phosphodiester bonds. Phosphodiester bonds are formed between the phosphate group of one nucleotide and the hydroxyl group at the 3’ end of another nucleotide, creating a continuous sugar-phosphate backbone that is essential for DNA structure and function.

Thus, when a lesion is repaired, the reconnection of these DNA segments involves reinforming the phosphodiester bonds, ensuring that the genetic information remains stable and correctly sequenced following repair.