What is the structure in the kidney where uric acid filtration occurs?

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Uric acid filtration occurs primarily in the nephron of the kidney, specifically within the renal corpuscle, which includes the glomerulus. The glomerulus is a network of capillaries where blood filtration initially takes place. During this process, waste products such as uric acid, along with water, electrolytes, and other small molecules, are filtered from the blood through the glomerular filtration barrier into the Bowman's capsule.

The nephron, as a whole, consists of a renal corpuscle (which contains the glomerulus) and a renal tubule (which includes the proximal convoluted tubule, loop of Henle, distal convoluted tubule, and collecting duct). It is important to note that while initial filtration occurs in the glomerulus, further processing of the filtered fluid, including reabsorption and secretion of substances such as uric acid, happens in the distal convoluted tubule and collecting duct.

Thus, while the glomerulus is where the initial filtration occurs, the entire nephron configuration is what facilitates the further management of uric acid in the kidney's functioning and plays a critical role in the overall process of homeostasis.

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