What is the primary mechanism through which increased temperature affects blood vessels during septic shock?

In septic shock, the body experiences a severe systemic inflammatory response to infection, leading to changes in blood vessel behavior. Increased temperature commonly associated with infections promotes vasodilation, which is the widening of blood vessels. This mechanism is primarily a response to the inflammatory mediators released during sepsis, such as histamines and prostaglandins.

The increased temperature leads to several physiological changes. Vasodilation occurs as the body attempts to enhance blood flow to tissues, aiding in the delivery of immune cells and nutrients critical for fighting the infection. Additionally, the increase in blood flow helps dissipate heat, as the body tries to regulate its temperature. This process results in symptoms such as flushed skin and can contribute to the development of hypotension (low blood pressure) common in septic shock, as the widening of blood vessels leads to a drop in vascular resistance.

This understanding is important when examining the overall effects of sepsis on the cardiovascular system and can guide appropriate medical interventions to manage blood pressure and circulation during this critical condition.