The collecting duct is responsive to which hormones?

The collecting duct in the nephron of the kidney is indeed responsive to both aldosterone and antidiuretic hormone (ADH), making the response that includes both hormones correct.

Aldosterone is a steroid hormone produced by the adrenal cortex that primarily acts on the distal convoluted tubule and the collecting duct. It promotes the reabsorption of sodium (Na+) and the secretion of potassium (K+). The reabsorption of sodium increases water reabsorption due to osmosis, which can lead to an increase in blood volume and blood pressure.

Antidiuretic hormone (ADH), also known as vasopressin, is produced in the hypothalamus and released by the posterior pituitary gland. ADH acts on the collecting duct by promoting the insertion of aquaporin-2 water channels into the membrane of the duct's principal cells. This allows for increased water reabsorption back into circulation, thereby concentrating the urine and reducing urine output.

The combined actions of these hormones facilitate the regulation of water balance and electrolyte homeostasis in the body. Consequently, the collecting duct's responsiveness to both aldosterone and ADH plays a significant role in maintaining fluid balance and blood pressure.