If the membrane potential of a cell changes from -60 mV to -70 mV due to an adrenergic drug, which ion channel is likely involved?

When the membrane potential of a cell changes from -60 mV to -70 mV, this indicates a hyperpolarization of the cell. Hyperpolarization occurs when the inside of the cell becomes more negatively charged relative to the outside.

The involvement of potassium channels is significant in this context because opening potassium channels allows potassium ions (K+) to flow out of the cell. As K+ ions exit, the inside of the cell loses positive charge, which increases the negativity of the membrane potential. Therefore, a change from -60 mV to -70 mV is typically associated with the activity of potassium channels.

In addition, adrenergic drugs often work by influencing the activity of various neurotransmitter systems, and their effects can include the opening of potassium channels, which can lead to hyperpolarization of the cell. This characteristic reinforces the idea that potassium channels can facilitate a shift in the membrane potential toward a more negative value.

While sodium and calcium channels typically contribute to depolarization (making the inside of the cell less negative), chloride channels can also lead to hyperpolarization under certain conditions. However, the primary pathway leading to a hyperpolarized state within the range provided is through the efflux of potassium ions, making potassium channels the most